Measures
In 2015 an FDA/NEI Working Group proposed the following as the five most important signs of disease activity:
- Vitreous Haze
- Retinal infiltrates
- Choroidal infiltrates
- Retinovascular leakage
- Anterior Chamber Cells
Currently all these signs of inflammation are assessed subjectively by the observing clinician, reducing the reliability and accuracy of these assessments. The aims of EQUATΘR are to develop techniques for objective quantification of each of these components of uveitis activity which will enable more accurate and reliable measurement of disease and response to treatment for both routine clinical use and as an endpoint in clinical trials.